Pemeriksaan Serologis IgG-IgM pada Pasien Demam Berdarah Dengue di RSUD Dr. Chasan Basoeri Ternate Periode Oktober - Desember 2021
Abstract
Dengue Fever (DF) is a viral infectious disease that is transmitted through the bite of the female Aedes aegypti and Aedes albopictus mosquitoes. This virus is a single-stranded RNA virus in the genus Flavivirus of the family Flaviviridae which has 4 serotypes (DEN-1, DEN-2, DEN-3, DEN-4). Indonesia is one of the dengue endemic countries. North Maluku is currently one of the provinces that are endemic for dengue fever. DF cases appear almost every year in North Maluku, especially in the city of Ternate. This study is a descriptive cross-sectional study to determine the distribution of samples based on gender, age, and serological examination of IgM-IgG antidengue antibodies in patients infected with dengue virus in RSUD DR. Chasan Basoeri Ternate period October to December 2021. The study was conducted on 12 patients. The results of this study showed that the most gender on serological examination, namely male sex more than female sex, namely as many as 7 patients (58.3%). The highest age range was 6-10 years as many as 7 patients (58.3%). The results of the IgM (+) IgG (-) examination were 3 patients (25%) in the age range of 6 to 10 years. The results of the IgM(-) IgG (+) examination were also 3 patients (25%) and IgM (+) IgG (+) as many as 1 patient (18.3%) in the age range of 6 to 10 years.
Keywords: Dengue Fever, serology, IgG, IgM.
Full Text:
PDFReferences
Arifin, N. F., Adi, M. S., & Suhartono, S. 2017. Analisis spasial dan temporal demam berdarah dengue di Kota Tanjungpinang tahun 2016. Universitas Diponegoro. [cited 2021 July 8]. Available from: http://eprints.undip.ac.id/61460/1/NUR_FITRIANA_ARIFIN_JURNAL_UNDIP.pdf
Candra, A. 2010. Demam Berdarah Dengue: Epidemiologi, Patogenesis, dan Faktor Risiko Penularan. Ciamis: Jurnal Aspirator Volume 2 Nomor 2.
Changal KH, Raina AH, Raina A, Raina M, Bashir R, Latief M et al. 2016. Differentiating secondary from primary dengue using IgG to IgM ratio in early dengue: An observational hospital based clinicoserological study from North India. India: BMC Infect Dis.
Cogan JE, WHO. 2007. Dengue and Severe Dengue. World Health Organisation.
Dardjito, E., Yuniarno, S., Wibowo, C., DL, A. S., & Dwiyanti, H. 2008. Beberapa Faktor Risiko yang Berpengaruh terhadap Kejadian Penyakit Demam Berdarah Dengue (DBD) di Kabupaten Banyumas. Jakarta: Media Penelitian dan Pengembangan Kesehatan Vol XVIII, No 3.
Dinkes Kota Ternate. 2019. Profil Kesehata Kota Ternate Tahun 2018. Ternate: Dinas Kesehatan Kota Ternate.
Enny Muchlastriningsih, Imran Ubis, Sri Susilowati, Diana Hutauruk, John Master Saragiha.1990. Gambaran Serologi Uji H.I. Pada Penderita Demam Berdarah Dengue Di Beberapa Rumah Sakit Dan Laboratorium Kesehatan Wilayah Jakarta Tahun 1990. Jakarta: Buletin Penelitian Kesehatan Penyakit Menular ; 21 (2) : 24-30
Irwadi D, Arif M, Hardjoeno. 2007. Gambaran Serologis IgM-IgG Cepat Dan Hematologi Rutin Penderita Dbd. Jakarta: Indonesian Journal Of Clinical Pathology And Medical Laboratory ; Vol. 13, No. 2.
Yohan B. 2018. Demam Berdarah Dengue: Problematika Interasi Virus, Pejamu, Vektor. Jakarta: Ejikman Institute for molecular biology.
Kasman K, Ishak N. 2018. Analisis Penyebaran Penyakit Demam Berdarah Dengue di Kota Banjarmasin tahun 2012- 2016. Banjarmasin: Media Publikasi Promosi Kesehatan Indonesia 1(2): 32–39.
Kementerian Kesehatan RI. 2020. Profil Kesehatan Indonesia Tahun 2019 [Internet]. Jakarta: Kemenkes [cited 2021 July 8]. Available from: https://pusdatin.kemkes.go.id/resources/downlo ad/pusdatin/profil-kesehatan-indonesia/ProfilKesehatan-Indonesia-2019.pdf
Kurniawan, M. 2015. Faktor Risiko Kejadian Syok Pada Pasien Demam Berdarah Dengue (DBD) Di RS PKU Muhammadiyah Yogyakarta Unit II, Thesis, Yogyakarta: Universitas Gadjah Mada. [cited 2021 Augstus 1 ].Avalible from http://etd.repository.ugm.ac.id/penelitian/detail/95766
Mahasurya Et Al. 2017. Gambaran Pemeriksaan Serologi IgM-IgG Antidengue Pasien Terinfeksi Virus Dengue Di Rumah Sakit Surya Husada Denpasar Bali Pada Periode Desember 2013 Sampai Mei 2014. Bali: Jurnal Medika,Vol 6 No 1
Permatasari, Y et al. 2015. Hubungan Status Gizi, Umur, dan Jenis Kelamin dengan Derajat Infeksi Dengue Pada Anak Devi. Semarang: Jurnal Kedokteran Muhammadiyah Volume 2 Nomor 1.
Sekaran SD, Lan EC, Subramaniam. 2008. Comparison of Five Serological Diagnostic Assay for Detection of IgM and IgG Antibodies to Dengue Virus. African Journal of Microbiology. 2008;2:141-147
Smith AW, Schwartz. 2005. Dengue in Travelers. New England Journal Medicine ; 353 : 925-932.
Soedarmo, S. S. P., Garna, H., Hadinegoro, S. R. S. & Satari, H. I. 2012. Buku Ajar Ilmu Kesehatan Anak: Infeksi & Pediatri Tropis. Edisi II Cetakan III ed. Jakarta: Badan Penerbit IDAI.
Statistik BP. 2019. Kota Ternate Dalam Angka 2019. Ternate. BPS Kota Ternate.
Suryani ET. 2018. Gambaran Kasus Demam Berdarah Dengue Di Kota Blitar Tahun 2015-2017. Surabaya: Jurnal Berkala Epidemiologi Unair.
Taufik A, Yudhanto D, Wajdi F, Rohadi. 2007. Peranan Kadar Hematokrit, Jumlah Trombosit dan Serologi IgG-IgM antiDHF dalam Memprediksi Terjadinya Syok pada Pasien Demam Berdarah Dengue (DBD) di Rumah Sakit Islam Siti Hajar Mataram. Mataram: Jurnal Penyakit Dalam Vol. 8
Tomia, S et al. 2020. Epidemiologi Kejadian Demam Berdarah Dengue di Kota Ternate. Maluku Utara. Bogor: Jurnal Veteriner Desember 2020 Vol. 21 No. 4 : 637-645.
Verdonschot PFM, Lototskaya AAB. 2014. Flight distance of mosquitoes (Culicidae): A metadata analysis to support the management or barrier zones around rewetted and newly constructed wetlands. Limnologica 45: 69-79.
Wangsa et al. 2015. Gambaran Serologis IgG-IgM pada Pasien Demam Berdarah di RSUP Sanglah Periode Juli-Agustus 2014. Bali: E-Jurnal Medika Udayana Vol 4, No1.
DOI: http://dx.doi.org/10.30829/jumantik.v7i2.11294
Refbacks
- There are currently no refbacks.
Copyright (c) 2022 Nia Kurnia
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.